One fateful day, all of humanity turned to stone. Many millennia later, Taiju frees himself from the petrification and finds himself surrounded by statues. The situation looks grim--until he runs into his science-loving friend Senku! Together they plan to restart civilization with the power of science!

The Kingdom of Science is off on a high-seas voyage to the U.S.A. However, Senku and Ryusui are soon divided on how best to chart their course, leading to all-out war--in the form of a poker game! After the winner is determined, what awaits their crew on the large continent to the east?!