ged remains of several dozen young men from a small Chicago ranch home and paraded them in front of a crowd of TV reporters and spectators, attention quickly turned to the owner of the house. John Gacy was an upstanding citizen, active in local politics and charities, famous for his themed parties and appearances as Pogo the Clown. But in the winter of 1978-79, he became known as one of many so-called "sex murderers" who had begun gaining notoriety in the random brutality of the 1970s.

As public interest grew rapidly, victims became footnotes and statistics, lives lost not just to violence, but to history. Through the testimony of siblings, parents, friends, lovers, and other witnesses close to the case, Boys Enter the House retraces the footsteps of these victims as they make their way to the doorstep of the Gacy house itself. Amid the ragged streets of the Uptown neighborhood, Samuel Stapleton and Randy Reffett play out a boyhood rivalry across gangs and girls that turns into a long-lasting friendship. Frank "Dale" Landingin and Billy Carroll attempt to break free of turbulent family lives, but find themselves navigating the gay underworld to get ahead. On the eve of starting their own lives, Gregory Godzik and Johnny Szyc juggle jobs and relationships as their paths gradually lead them to the home at 8213 Summerdale Avenue.

United by one man's act of depravity, these victims will step forward to share boyish dreams of love and sex, family tragedies of abuse and addiction, and adolescent journeys through the neighborhoods of Chicago and the vibrant decade of the 1970s.