1897, London. The capital is shocked to learn that the body of a woman has been found at the National Gallery, eviscerated in a manner that recalls all too strongly the exploits of Jack the Ripper.

The Museum Detectives Daniel Wilson and Abigail Fenton are contacted by a curator of the Gallery for their assistance. The dead woman, a lady of the night, had links to artist Walter Sickert who was a suspect during the Ripper's spree of killings. Scotland Yard have arrested Sickert on suspicion of this fresh murder but it is not the last.

Copycat murders of the Ripper's crimes implicate the artist who loves to shock but Sickert insists that he is innocent. Wilson and Fenton have their work cut out catching an elusive and determined killer.