Resembling the complex and fragmented way a fly's eye works, Natural Novel contains a myriad of storylines, reflections, and digressions, including a history of toilets and the graffiti found there, a meditation on the relationship between bees and language, and an attempt to write a book using only verbs.

Incredibly funny at times, this novel is driven by the narrator's need to come to terms with his dissolving marriage and his wife's infidelity with their close friend. Gospodinov's first novel is both broad in scope and intensely personal, illustrating the impossibility of presenting life truthfully.